In vitro structure-toxicity relationship of chalcones in human hepatic stellate cells
نویسندگان
چکیده
منابع مشابه
In vitro reversion of activated primary human hepatic stellate cells
BACKGROUND Liver fibrosis is characterized by the excessive formation and accumulation of matrix proteins as a result of wound healing in the liver. A main event during fibrogenesis is the activation of the liver resident quiescent hepatic stellate cell (qHSC). Recent studies suggest that reversion of the activated HSC (aHSC) phenotype into a quiescent-like phenotype could be a major cellular m...
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ژورنال
عنوان ژورنال: Toxicology
سال: 2015
ISSN: 0300-483X
DOI: 10.1016/j.tox.2015.07.012